Quotable Quote: Science Fraud

The Powerline blog has been publishing a series looking at fraud in science--specifically, underlying papers published in scientific journals. A recent article included the following quotation from Richard Horton, the editor of The Lancet:

The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue. Afflicted by studies with small sample sizes, tiny effects, invalid exploratory analyses, and flagrant conflicts of interest, together with an obsession for pursuing fashionable trends of dubious importance, science has taken a turn towards darkness. . .

(Underline added). (See also Retraction Watch, which attempts to document retractions made by science journals).