The Spread of Antiobiotic Resistant Bacterial Infections

To sum it up: too free of use of antibiotics. From Spiegel Online:

Microbiologists refer to this bacterium as community-acquired methicillin-resistant Staphylococcus aureus, or ca-MRSA. The terrifying thing about it is its resistance to almost all common antibiotics, which complicates treatment. And, in contrast to the highly drug-resistant hospital-acquired MRSA (ha-MRSA) strains, which primarily affect the elderly and people in hospitals and nursing homes, ca-MRSA affects healthy young people. The bacterium has become a serious health threat in the United States. Doctors have already discovered it in Germany, although no deaths have been attributed to it yet in the country.

The two bacteria, ha-MRSA and ca-MRSA, are only two strains from an entire arsenal of pathogens that are now resistant to almost all available antibiotics. Less than a century after the discovery of penicillin, one of the most powerful miracle weapons ever produced by modern medicine threatens to become ineffective.

The British medical journal The Lancet warns that the drug-resistant bacteria could spark a "pandemic." And, in Germany, the dangerous pathogens are no longer only feared "hospital bugs" found in intensive care units (ICUs). Instead, they have become ubiquitous.

About two weeks ago, consumers were alarmed by the results of an analysis of chicken meat by the environmentalist group Friends of the Earth Germany (BUND), which found multidrug-resistant bacteria on more than half of the chicken parts purchased in supermarkets.

The dangerous bacteria have even been detected on one of Germany's high-speed ICE trains. Likewise, more than 10 percent of the residents of German retirement homes have been colonized by MRSA bacteria. In their case, every open wound is potentially deadly. The pathogens have also been found on beef, pork and vegetables.

Another alarming finding is that about 3 to 5 percent of the population carries so-called ESBL-forming bacteria in the intestine without knowing it. Even modern antibiotics are completely ineffective against these highly resistant bacteria.

Diminishing Defenses

When the neonatal ICU at a hospital in the northern German city of Bremen was infested with an ESBL-forming bacterium last fall, three prematurely born babies died.

Infestation with multidrug-resistant bacteria is normally harmless to healthy individuals because their immune systems can keep the pathogens under control. Problems arise when an individual becomes seriously ill.

"Take, for example, a person who is having surgery and requires artificial respiration and receives a venous or urinary catheter," explains Petra Gastmeier, director of the Institute of Hygiene and Environmental Medicine at Berlin's Charité Hospital. "In such a case, the resistant intestinal bacteria can enter the lungs, the bloodstream and the bladder."

This results in urinary tract infections, pneumonia or sepsis, which are increasingly only treatable with so-called reserve antibiotics, that is, drugs for emergencies that should only be administered when common antibiotics are no longer effective.

The Spread of Killer Bugs

Recently, an even greater threat has arisen. With the spread of ESBL-forming bacteria, reserve antibiotics have to be used more and more frequently, thereby allowing new resistances to develop. In fact, there are already some pathogens that not even the drugs of last resort in the medical arsenal can combat.


In India, where poor hygiene and the availability of over-the-counter antibiotics encourage the development of resistance, an estimated 100 to 200 million people are reportedly already carriers of these virtually unbeatable killer bacteria. There is only one antibiotic left -- a drug that is normally not even used anymore owing to its potentially fatal side effects -- that is still effective against these killer bacteria. In serious cases, people who become infected with these types of pathogens die of urinary tract infections, wound infections or pneumonia.

The killer bugs have also reached England, presumably through medical tourists who traveled to India for cosmetic surgery, and they have reportedly already infected several hundred people. A few cases have also turned up in Germany.

Israel even experienced a nationwide outbreak a few years ago. Within a few months, about 1,300 people were afflicted by an extremely dangerous bacterium that killed 40 percent of infected patients. Even today, the same bacterium still sickens some 300 people a year.

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