A decade after SARS swept through the world and killed more than 750 people, scientists have made a troubling discovery: A very close cousin of the SARS virus lives in bats and it can likely jump directly to people.
The findings create new fears about the emergence of diseases like SARS, or severe acute respiratory syndrome. The virus spread quickly from person to person in 2003 and had a mortality rate of at least 9%. ...
While bats have previously been fingered as a host for SARS, it was believed that the virus jumped from there to weasel-like mammals known as civets, where it went through genetic changes before infecting people. Operating on that belief, China cracked down on markets where bats, civets and other wildlife were sold for food.
The new bat-to-human discovery suggests that the control tactic may have limited effectiveness because a SARS-like virus remains loose in the wild and could potentially spark another outbreak.
... "This paper indicates that the bat is the origin and that the virus can be directly transmitted to humans," said Charles Calisher, a virologist at Colorado State University who wasn't involved in the study. "It practically rules out the possibility" of an intermediate host.
Dr. Daszak described a potential scenario where close contact between bats and humans—such as when the animals are captured for food—could increase the risk of viral transmission. "They are bringing wildlife in from new areas. They are going to Yunnan where bats are still common."
Dr. Calisher said the finding was important because researchers will now be able to get clues about the danger these novel SARS-like coronaviruses pose. For example, if a bat carries a high load of the virus, it indicates that the potential for transmission to humans is also high.
... there is strong evidence that bats are a natural reservoir for a host of dangerous viruses, including Ebola, Nipah and SARS.
A year ago, scientists reported the emergence of a novel coronavirus, called Middle East Respiratory Syndrome, or MERS. It has since been reported in people in several countries, including Saudi Arabia, Germany, France, Italy, Britain and other parts of the Persian Gulf. Oman reported its first case on Wednesday, according to local reports.
In July, a WHO committee concluded that while MERS was of "serious and great concern," it wasn't a global health emergency. Research has suggested local bats may be a host for MERS, though the findings aren't definitive.
Nonetheless, the authors of the Nature study noted that the outbreak in the Middle East "suggests that this group of viruses remains a key threat and that their distribution is wider than previously recognized."
Thursday, October 31, 2013
Bat to Human Transmission of SARS
From the Wall Street Journal:
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